Opko: Revenue Rose 4.3% - and Excluding One Non-Recurring Line It Fell 14.5%

Results published 27 July 2026. Opko reported revenue of $163.5 million, up 4.3%, and an operating loss narrowing from $60 million to $7 million - an improvement that looks dramatic. But inside revenue sit $29.4 million of shares received in a transaction, and inside the diagnostics arm sits an $18.1 million Labcorp earnout. Excluding both, revenue fell 14.5% and the operating loss stands at roughly $54.5 million. The full breakdown.

By Ilan Abramov4 min read
Opko: Revenue Rose 4.3% - and Excluding One Non-Recurring Line It Fell 14.5%
* The cover image was generated with an AI tool and is not a photograph.

These results were published on Monday, 27 July 2026, after the US close. We cover them here to complete the picture.

Opko reported a quarter that looks like a turning point - and most of the improvement comes from two non-recurring lines.

What was reported

QuarterYear agoChange
Revenue163.5156.8+4.3%
Operating loss-7.0-60.0narrowed 88%
Net loss-8.4-148.4narrowed 94%
EPS-$0.01-$0.19-

In millions of dollars

At first glance: a reversal. The net loss narrowed 94%, and revenue grew.

And at second glance

▼דובי

Two lines that change the picture

First: $29.4 million of quarterly revenue is recognition of shares received from Nicoya - not a sale of a service or product.

Excluding it, revenue stands at $134.1 million - a fall of 14.5%, rather than a rise of 4.3%.

And second: the diagnostics arm posted a first operating profit of $4.8 million - but it includes an $18.1 million earnout from Labcorp, which offset operating expenses.

Excluding both items together, the operating loss stands at roughly $54.5 million - rather than the $7.0 million reported. Which means the improvement against $60.0 million a year ago is about five million, not 53.

The breakdown

SegmentQuarterYear agoChange
Services (diagnostics)74.5101.1-26.3%
Products (pharmaceuticals)42.940.7+5.4%
Intellectual property and other46.115.0+207%

In millions of dollars

The 26.3% diagnostics decline is not operational deterioration - it stems largely from the September 2025 sale of oncology diagnostics assets to Labcorp. The company sold part of the business, so revenue is smaller.

And the 207% jump in intellectual property is mostly those same $29.4 million of Nicoya shares.

What genuinely improves

Cash burn. Net cash used in operating activities in the first half fell to $62.8 million, from $118.0 million - a cut of roughly 47%.

This is the figure hardest to dress up, and it points to real operational improvement independent of one-off lines.

On the balance sheet: $314.4 million in cash and securities at 30 June, down $54.7 million from end-2025.

And buybacks: $13.2 million in the quarter, and $105.3 million cumulative. Roughly $94.7 million remains authorised.

Guidance - raised

Full-year revenue: raised to $560-585 million, from $530-560 million. And the expense budget was actually lowered to $710-740 million from $725-750 million.

But it is worth noting where the quarterly beat came from: the $163.5 million result exceeded the company's own guidance of $127-132 million - and almost the entire difference comes from the intellectual property line, which delivered $46.1 million against the $15-19 million guided.

And the asset growing quietly

Opko's share of NGENLA profits - the growth hormone marketed by Pfizer - reached $6.4 million in the quarter and $12.8 million in the half. Full-year guidance: $34-37 million.

And Rayaldee brought in $8.1 million, up 12.5%.

My Angle

A personal opinion of Ilan Abramov - not advice, not a recommendation

Opko is a good exercise in reading a company selling assets while attempting a turnaround.

Every headline number is affected by a transaction rather than by operations. Revenue rose because of shares received; diagnostics fell because of assets sold; the operating loss narrowed because of an earnout. None of them is a lie, and none of them describes the ongoing business.

The only number that does describe it is the cash burn - down from $118 million to $62.8 million in half a year. That is a real decline, and it is the most important thing in the report.

And what I file under questions: guidance was raised, but the quarterly beat came almost entirely from intellectual property - a line that by its nature does not recur at a steady pace. Next quarter will show whether the operating base has genuinely stabilised.